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    Of 27, articles identified, 17 eligible studies were included. We pooled independent study estimates using random-effects models. In leave-one-out sensitivity analyses pooled estimates were generally robust to removing individual study estimates. Main limitations included poor exposure definition, incomplete adjustment for confounders, particularly condom use, and use of non-confidential interview methods. More and better data are needed to explain differences in risk by world region and risk population.
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    Complete anal sphincter complex disruption from intercourse: A case report and literature review

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    Complete anal sphincter complex disruption from intercourse: A case report and literature review

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    Anal sphincter injuries are uncommon injuries outside of obstetric practice — but they may cause disastrous complications. We present a case of complete anal sphincter disruption from anal intercourse in a 25 year old woman. Clinical management is presented and technical details of the repair are discussed.
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    Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Here, we performed a comprehensive characterization of the rectal mucosal immune environment for the phenotype and production of pro-inflammatory cytokines by CD4 and CD8 T cells, global transcriptomic analyses, and the composition of microbiota in HIV-negative MSM.
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